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In some cases, imagingof the spine is useful for identifying obstructive causesfor hydrocephalus. Substance misuseon site has added to this role and brought an illicit drug culture into psychiatric settings (to addto the official pre-existing one of prescribed medication routines). Fructose enters thecell via facilitated Na+-independent transport using GLUT5 {gray circlewith Flabel) and GLUT2 glucose transporters {orange octagon with G2label). Neuropathologic studies also show age-relatedwhite matter changes (Moody et al., 1995; Fernandoet al., 2006; Simpson et al., 2009), with changes in mul-tiple functional pathways (Simpson et al., 2009) and apossible relationship with chronic hypoperfusion (Fer-nando et al., 2006). Overall, there were improvements in activities of dailyliving, Unified Parkinson Disease Rating Scale (UPDRS) and Schwab andEngland Activities of Daily Living Scale for Coenzyme Q10 at 1,200 mg/day for sixteen months versus placebo

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